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Table of Contents | 117(3): Mar 2009

On the Cover

The scientific community generates an unprecedented volume of data about potential hazards to the environment and human health, but the process of interpretation remains in the hands of political, economic, and even cultural interests, which can vary dramatically from one hazard to the next, as well as from one jurisdiction to the next. This article (p. A104) describes how a given agent might be labeled a toxic threat in one place while being tolerated without prejudice somewhere else, even as the architects of each policy looked at the very same data.

Image Credit: Dave Cutler/Images.com

 

 

 

Editorial

Bisphenol A: Where to Now?

John R. Bucher, NTP, NIEHS

 

Correspondence

RDX and miRNA Expression in B6C3F1 Mice

Desmond I. Bannon, Mark Johnson, Larry Williams, Valerie Adams, Edward Perkins, Kurt Gust, Ping Gong

RDX and miRNA Expression: Zhang and Pan Respond

Baohong Zhang, Xiaoping Pan

Don’t Flush the Yuck Factor

John Manuel

 

News | Forum

Smoking Bans Yield Long-Term Benefits

Adrian Burton

Developmental Picture Window

Julia R. Barrett

Phosphate Linked to Lung Cancer in Mice

Carol Potera

The Beat

Erin E. Dooley

California’s 2020 Vision

Graeme Stemp-Morlock

 

News | Focus

Outside Looking In: Understanding the Role of Science in Regulation

Tim Lougheed

 

News | Spheres of Influence

Building on Success: Assessment Categories for Experimental Noncancer End Points

Bob Weinhold

 

News | Science Selections

Tough Call: Challenges to Assessing Cancer Effects of Mobile Phone Use

M. Nathaniel Mead

Protein Baggage: Toxicity of Organotin Tied to Proteasome Interference

M. Nathaniel Mead

From Dust to Blood: Studies Predict Lead Intake in Children

Rebecca Kessler

Synergy for Salmon: Study Spawns Insight into Pesticide Mixtures

Bob Weinhold

 

Commentary

Why Public Health Agencies Cannot Depend on Good Laboratory Practices as a Criterion for Selecting Data: The Case of Bisphenol A

John Peterson Myers, Frederick S. vom Saal, Benson T. Akingbemi, Koji Arizono, Scott Belcher, Theo Colborn, Ibrahim Chahoud, D. Andrew Crain, Francesca Farabollini, Louis J. Guillette Jr., Terry Hassold, Shuk-mei Ho, Patricia A. Hunt, Taisen Iguchi, Susan Jobling, Jun Kanno, Hans Laufer, Michele Marcus, John A. McLachlan, Angel Nadal, Jörg Oehlmann, Nicolás Olea, Paola Palanza, Stefano Parmigiani, Beverly S. Rubin, Gilbert Schoenfelder, Carlos Sonnenschein, Ana M. Soto, Chris E. Talsness, Julia A. Taylor, Laura N. Vandenberg, John G. Vandenbergh, Sarah Vogel, Cheryl S. Watson, Wade V. Welshons, R. Thomas Zoeller

Editor's Summary

 

Reviews

Manganese Neurotoxicity: Lessons Learned from Longitudinal Studies in Nonhuman Primates

Neal C. Burton, Tomás R. Guilarte

Editor's Summary

The Controversy about a Possible Relationship between Mobile Phone Use and Cancer

Michael Kundi

Editor's Summary

 

Research Articles

The Effects of Fine Particle Components on Respiratory Hospital Admissions in Children

Bart Ostro, Lindsey Roth, Brian Malig, Melanie Marty

Editor's Summary

Variability in Biomarkers of Arsenic Exposure and Metabolism in Adults over Time

Molly L. Kile, Elaine Hoffman, Yu-Mei Hsueh, Sakila Afroz, Quazi Quamruzzaman, Mahmuder Rahman, Golam Mahiuddin, Louise Ryan, David C. Christiani

Editor's Summary

The Synergistic Toxicity of Pesticide Mixtures: Implications for Risk Assessment and the Conservation of Endangered Pacific Salmon

Cathy A. Laetz, David H. Baldwin, Tracy K. Collier, Vincent Hebert, John D. Stark, Nathaniel L. Scholz

Editor's Summary

Exposure of U.S. Children to Residential Dust Lead, 1999–2004: I. Housing and Demographic Factors

Joanna M. Gaitens, Sherry L. Dixon, David E. Jacobs, Jyothi Nagaraja, Warren Strauss, Jonathan W. Wilson, Peter J. Ashley

Editor's Summary

Exposure of U.S. Children to Residential Dust Lead, 1999–2004: II. The Contribution of Lead-Contaminated Dust to Children’s Blood Lead Levels

Sherry L. Dixon, Joanna M. Gaitens, David E. Jacobs, Warren Strauss, Jyothi Nagaraja, Tim Pivetz, Jonathan W. Wilson, Peter J. Ashley

Editor's Summary

A Physiologically Based Pharmacokinetic Model for the Assessment of Infant Exposure to Persistent Organic Pollutants in Epidemiologic Studies

Marc-André Verner, Pierre Ayotte, Gina Muckle, Michel Charbonneau, Sami Haddad

Editor's Summary

Lactational Exposure to Polychlorinated Biphenyls, Dichlorodiphenyltrichloroethane, and Dichlorodiphenyldichloroethylene and Infant Neurodevelopment: An Analysis of the Pregnancy, Infection, and Nutrition Babies Study

I-Jen Pan, Julie L. Daniels, Barbara D. Goldman, Amy H. Herring, Anna Maria Siega-Riz, Walter J. Rogan

Editor's Summary

Diesel Exhaust Particles Activate the Matrix-Metalloproteinase-1 Gene in Human Bronchial Epithelia in a β-Arrestin–Dependent Manner via Activation of RAS

Jinju Li, Andrew J. Ghio, Seung-Hyun Cho, Constance E. Brinckerhoff, Sidney A. Simon, Wolfgang Liedtke

Editor's Summary

The Proteasome Is a Molecular Target of Environmental Toxic Organotins

Guoqing Shi, Di Chen, Guangshu Zhai, Marina S. Chen, Qiuzhi Cindy Cui, Qunfang Zhou, Bin He, Q. Ping Dou, Guibin Jiang

Editor's Summary

Profiling Chemicals Based on Chronic Toxicity Results from the U.S. EPA ToxRef Database

Matthew T. Martin, Richard S. Judson, David M. Reif, Robert J. Kavlock, David J. Dix

Editor's Summary

Proximity to Traffic, Inflammation, and Immune Function among Women in the Seattle, Washington, Area

Lori A. Williams, Cornelia M. Ulrich, Timothy Larson, Mark H. Wener, Brent Wood, Peter T. Campbell, John D. Potter, Anne McTiernan, Anneclaire J. De Roos

Editor's Summary

Methylmercury Exposure and Adverse Cardiovascular Effects in Faroese Whaling Men

Anna L. Choi, Pal Weihe, Esben Budtz-Jørgensen, Poul J. Jørgensen, Jukka T. Salonen, Tomi-Pekka Tuomainen, Katsuyuki Murata, Hans Petur Nielsen, Maria Skaalum Petersen, Jórun Askham, Philippe Grandjean

Editor's Summary

Short-Term Mortality Rates during a Decade of Improved Air Quality in Erfurt, Germany

Susanne Breitner, Matthias Stölzel, Josef Cyrys, Mike Pitz, Gabriele Wölke, Wolfgang Kreyling, Helmut Küchenhoff, Joachim Heinrich, H.-Erich Wichmann, Annette Peters

Editor's Summary

Public Health Strategies for Western Bangladesh That Address Arsenic, Manganese, Uranium, and Other Toxic Elements in Drinking Water

Seth H. Frisbie, Erika J. Mitchell, Lawrence J. Mastera, Donald M. Maynard, Ahmad Zaki Yusuf, Mohammad Yusuf Siddiq, Richard Ortega, Richard K. Dunn, David S. Westerman, Thomas Bacquart, Bibudhendra Sarkar

Editor's Summary

Mechanisms of Inhaled Fine Particulate Air Pollution–Induced Arterial Blood Pressure Changes

Carlo R. Bartoli, Gregory A. Wellenius, Edgar A. Diaz, Joy Lawrence, Brent A. Coull, Ichiro Akiyama, Lani M. Lee, Kazunori Okabe, Richard L. Verrier, John J. Godleski

Editor's Summary

Exposure to Mouse Allergen in U.S. Homes Associated with Asthma Symptoms

Päivi M. Salo, Renee Jaramillo, Richard D. Cohn, Stephanie J. London, Darryl C. Zeldin

Editor's Summary

Apparent Half-Lives of Dioxins, Furans, and Polychlorinated Biphenyls as a Function of Age, Body Fat, Smoking Status, and Breast-Feeding

Meghan O’Grady Milbrath, Yvan Wenger, Chiung-Wen Chang, Claude Emond, David Garabrant, Brenda W. Gillespie, Olivier Jolliet

Editor's Summary

Elevated Human Telomerase Reverse Transcriptase Gene Expression in Blood Cells Associated with Chronic Arsenic Exposure in Inner Mongolia, China

Jinyao Mo, Yajuan Xia, Zhixiong Ning, Timothy J. Wade, Judy L. Mumford

Editor's Summary

Neighborhood Food Environment and Walkability Predict Obesity in New York City

Andrew Rundle, Kathryn M. Neckerman, Lance Freeman, Gina S. Lovasi, Marnie Purciel, James Quinn, Catherine Richards, Neelanjan Sircar, Christopher Weiss

Editor's Summary

Impact of the Spanish Smoking Law on Exposure to Secondhand Smoke in Offices and Hospitality Venues: Before-and-After Study

Manel Nebot, Maria J. López, Carles Ariza, Mónica Pérez-Ríos, Marcela Fu, Anna Schiaffino, Gloria Muñoz, Esteve Saltó, Esteve Fernández

Editor's Summary

Activated Toxicity of Diesel Particulate Extract by Ultraviolet A Radiation in Mammalian Cells: Role of Singlet Oxygen

Lingzhi Bao, An Xu, Liping Tong, Shaopeng Chen, Lingyan Zhu, Ye Zhao, Guoping Zhao, Erkang Jiang, Jun Wang, Lijun Wu

Editor's Summary

Developmental Exposure to Polychlorinated Biphenyls Interferes with Experience-Dependent Dendritic Plasticity and Ryanodine Receptor Expression in Weanling Rats

Dongren Yang, Kyung Ho Kim, Andrew Phimister, Adam D. Bachstetter, Thomas R. Ward, Robert W. Stackman, Ronald F. Mervis, Amy B. Wisniewski, Sabra L. Klein, Prasada Rao S. Kodavanti, Kim A. Anderson, Gary Wayman, Isaac N. Pessah, Pamela J. Lein

Editor's Summary

Concentrated Ambient Particles Alter Myocardial Blood Flow during Acute Ischemia in Conscious Canines

Carlo R. Bartoli, Gregory A. Wellenius, Brent A. Coull, Ichiro Akiyama, Edgar A. Diaz, Joy Lawrence, Kazunori Okabe, Richard L. Verrier, John J. Godleski

Editor's Summary

Ultraviolet Photolysis of Chlorpyrifos: Developmental Neurotoxicity Modeled in PC12 Cells

Theodore A. Slotkin, Frederic J. Seidler, Changlong Wu, Emiko A. MacKillop, Karl G. Linden

Editor's Summary

 

Book Review

Book Review: Oceans and Human Health: Risks and Remedies from the Sea

D. Jay Grimes

 

New Books

New Books